147 Barrier Cream
1% madecassoside + 4% niacinamide + 7% panthenol — active treatment cream for barrier and tone.
About this product
Dr. Althea 147 Cream is a targeted treatment moisturiser centred on three key actives at clinically meaningful concentrations: 1% madecassoside (concentrated centella asiatica extract), 4% niacinamide, and 7% panthenol. This precise combination targets three interconnected skin concerns simultaneously — redness and barrier inflammation (madecassoside), sebum regulation and hyperpigmentation (niacinamide), and intensive moisture barrier recovery (panthenol). The lightweight gel-cream texture suits oily and combination skin types seeking active treatment without heavy emollient feel.
Best for oily, combination, normal, sensitive skin looking to address redness, acne, hyperpigmentation — with a focus on soothing.
Product Attributes
pH Level
Mildly acidic — close to skin's natural pH (4.5–5.5). Generally well tolerated.
How to Use
- 1Apply morning and evening after toner and serum.
- 2Dispense a pea-sized amount and spread evenly across face and neck.
- 3The gel-cream texture absorbs quickly — suitable under sunscreen without heaviness.
- 4Can be used as a spot treatment on active blemishes or red patches.
Dermatologist Note
The 147 formulation is notable for its high panthenol concentration. Panthenol (provitamin B5) is converted in vivo to pantothenic acid, which plays a central role in fatty acid synthesis within keratinocytes — directly supporting lamellar body production and barrier lipid replenishment. At 7%, this is a therapeutically meaningful dose, with clinical data showing significant reduction in TEWL and improvement in stratum corneum cohesion (Ebner et al., 2002). Combined with madecassoside's anti-inflammatory action and niacinamide's sebum regulation, the 147 Cream is particularly effective for post-acne recovery and reactive skin.
Based on published clinical literature and dermatological research.
Ingredient Analysis
Full Ingredient List (INCI)
7 ingredientsListed in order of concentration (highest first)
Centella Asiatica Extract, Niacinamide, Panthenol, Hyaluronic Acid, Ceramide AP, Glycerin, Allantoin
No reviews yet. Be the first to review this product!