345 Relief Cream Renewed
Upgraded blemish cream with PDRN and Centella waters for enhanced repair and soothing
About this product
The Dr. Althea 345 Relief Cream Renewed is an evolved formula that swaps botanical extracts for more targeted bioactive complexes. 3 Blemish Care: Resveratrol protects against oxidative stress; Tannic Acid tightens pores and soothes with its astringent polyphenol action; Niacinamide controls sebum and visibly reduces dark spots. 4 Nourishing Care: Beta-Glucan builds a lasting moisture shield; Hydrolyzed Hyaluronic Acid penetrates deeply for cellular-level hydration; Ceramide NP restores the lipid barrier; Rice Bran PDRN accelerates skin regeneration at a cellular level. 5 Soothing Care: Camellia Sinensis (Green Tea) Leaf Water delivers antioxidant calm; Tea Tree Leaf Water purifies and reduces breakout-causing bacteria; Centella Asiatica Leaf Water soothes redness; Madecassoside (purified Cica) repairs the barrier; Centella Asiatica PDRN supercharges healing with cellular-level regeneration.
Best for dry, normal, combination, sensitive skin looking to address dryness, dehydration, fine lines & wrinkles — with a focus on barrier repair.
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How to Use
- 1Apply as the final step of your AM and PM routine.
- 2Take a pea-to-almond-sized amount and warm between fingertips.
- 3Press and pat gently into skin — the lighter texture absorbs faster than the original.
- 4Can be layered under sunscreen without pilling. Follow with SPF 30+ in the morning.
Product Claims
Common Allergens
Based on confirmed product attributes. Always check the full ingredient list for personal allergens.
Always check the full ingredient list if you have known allergies or sensitivities.
Routine Placement
Apply this cream as step 7 in your routine.
Quick Stats
Key Ingredients
Ingredient Analysis
Disclaimer: Ingredient information is for educational purposes only and does not constitute medical or dermatological advice. Sources: EWG Skin Deep, EU CosIng, NIH PubChem.
pH Level
Slightly acidic — close to skin's natural pH (4.5–5.5). Gentle and generally well tolerated.
Dermatologist Note
The Renewed formula is notably more repair-focused than the original — the addition of both Rice Bran PDRN and Centella Asiatica PDRN makes it better suited for post-breakout recovery, post-procedure care, or anyone with a compromised barrier. If you're dealing with active acne alongside sensitivity, this version offers stronger regenerative support.
Based on published clinical literature and dermatological research.
Ingredient Analysis
Disclaimer: Ingredient information is for educational purposes only and does not constitute medical or dermatological advice. Sources: EWG Skin Deep, EU CosIng, NIH PubChem.
Where to Buy
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Community Rating
Aggregated from public sourcesCan't tell the difference between the new version and the original, but it does keep me moisturized and have had no breakouts. The PDRN is a plus on the new version.
Disclaimer: Information on this page is for educational purposes only and does not constitute medical or dermatological advice. Always patch test new products and consult a qualified professional if you have skin concerns. Skinuity does not sell any products. We provide affiliate links to third-party retailers and may earn a commission on qualifying purchases.